Therapeutic actions of cyclosporine and anti-tumor necrosis factor alpha in collagen-induced arthritis and the effect of combination therapy.

Therapeutic actions of cyclosporine and anti-tumor necrosis factor alpha in collagen-induced arthritis and the effect of combination therapy.

OBJECTIVE: To define the mechanisms of action of 2 novel drugs, cyclosporine and anti-tumor necrosis factor alpha (TNFalpha), in collagen-induced arthritis and to determine the effect of combination therapy. METHODS: Type II collagen-immunized DBA/1 mice with established arthritis were treated with...

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Detalhes bibliográficos
Main Authors:	Williams, R, Mauri, C, Mason, L, Marinova-Mutafchieva, L, Ross, SE, Feldmann, M, Maini, R
Formato:	Journal article
Idioma:	English
Publicado em:	1998

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