The current role of MRI in differentiating multiple sclerosis from its imaging mimics
MRI red flags proposed over a decade ago by the European Magnetic Resonance Network in MS (MAGNIMS) have guided clinicians in the diagnosis of multiple sclerosis (MS). However, the past 10 years have seen increased recognition that vascular disease can coexist and possibly interact with MS, improvem...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Nature Publishing Group
2018
|
| _version_ | 1797095949455065088 |
|---|---|
| author | Geraldes, R Ciccarelli, O Barkhof, F De Stefano, N Enzinger, C Filippi, M Hofer, M Paul, F Preziosa, P Rovira, A De Luca, G Kappos, L Yousry, T Fazekas, F Frederiksen, J Gasperini, C Sastre-Garriga, J Evangelou, N Palace, J |
| author_facet | Geraldes, R Ciccarelli, O Barkhof, F De Stefano, N Enzinger, C Filippi, M Hofer, M Paul, F Preziosa, P Rovira, A De Luca, G Kappos, L Yousry, T Fazekas, F Frederiksen, J Gasperini, C Sastre-Garriga, J Evangelou, N Palace, J |
| author_sort | Geraldes, R |
| collection | OXFORD |
| description | MRI red flags proposed over a decade ago by the European Magnetic Resonance Network in MS (MAGNIMS) have guided clinicians in the diagnosis of multiple sclerosis (MS). However, the past 10 years have seen increased recognition that vascular disease can coexist and possibly interact with MS, improvements in the reliability of ways to differentiate MS from novel antibody-mediated CNS disorders (such as anti-aquaporin-4 antibody and myelin-oligodendrocyte glycoprotein antibody-associated diseases) and advances in MRI techniques. In this Review, MAGNIMS updates the imaging features that differentiate the most common mimics of MS, particularly age-related cerebrovascular disease and neuromyelitis optica, from MS itself. We also provide a pragmatic summary of the clinically useful MRI features that distinguish MS from its mimics and discuss the future of nonconventional techniques that have identified promising disease-specific features. |
| first_indexed | 2024-03-07T04:35:17Z |
| format | Journal article |
| id | oxford-uuid:cfb8a7b0-f275-441b-809a-3945cb7e2a0f |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:35:17Z |
| publishDate | 2018 |
| publisher | Nature Publishing Group |
| record_format | dspace |
| spelling | oxford-uuid:cfb8a7b0-f275-441b-809a-3945cb7e2a0f2022-03-27T07:44:41ZThe current role of MRI in differentiating multiple sclerosis from its imaging mimicsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:cfb8a7b0-f275-441b-809a-3945cb7e2a0fEnglishSymplectic Elements at OxfordNature Publishing Group2018Geraldes, RCiccarelli, OBarkhof, FDe Stefano, NEnzinger, CFilippi, MHofer, MPaul, FPreziosa, PRovira, ADe Luca, GKappos, LYousry, TFazekas, FFrederiksen, JGasperini, CSastre-Garriga, JEvangelou, NPalace, JMRI red flags proposed over a decade ago by the European Magnetic Resonance Network in MS (MAGNIMS) have guided clinicians in the diagnosis of multiple sclerosis (MS). However, the past 10 years have seen increased recognition that vascular disease can coexist and possibly interact with MS, improvements in the reliability of ways to differentiate MS from novel antibody-mediated CNS disorders (such as anti-aquaporin-4 antibody and myelin-oligodendrocyte glycoprotein antibody-associated diseases) and advances in MRI techniques. In this Review, MAGNIMS updates the imaging features that differentiate the most common mimics of MS, particularly age-related cerebrovascular disease and neuromyelitis optica, from MS itself. We also provide a pragmatic summary of the clinically useful MRI features that distinguish MS from its mimics and discuss the future of nonconventional techniques that have identified promising disease-specific features. |
| spellingShingle | Geraldes, R Ciccarelli, O Barkhof, F De Stefano, N Enzinger, C Filippi, M Hofer, M Paul, F Preziosa, P Rovira, A De Luca, G Kappos, L Yousry, T Fazekas, F Frederiksen, J Gasperini, C Sastre-Garriga, J Evangelou, N Palace, J The current role of MRI in differentiating multiple sclerosis from its imaging mimics |
| title | The current role of MRI in differentiating multiple sclerosis from its imaging mimics |
| title_full | The current role of MRI in differentiating multiple sclerosis from its imaging mimics |
| title_fullStr | The current role of MRI in differentiating multiple sclerosis from its imaging mimics |
| title_full_unstemmed | The current role of MRI in differentiating multiple sclerosis from its imaging mimics |
| title_short | The current role of MRI in differentiating multiple sclerosis from its imaging mimics |
| title_sort | current role of mri in differentiating multiple sclerosis from its imaging mimics |
| work_keys_str_mv | AT geraldesr thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT ciccarellio thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT barkhoff thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT destefanon thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT enzingerc thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT filippim thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT hoferm thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT paulf thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT preziosap thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT roviraa thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT delucag thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT kapposl thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT yousryt thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT fazekasf thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT frederiksenj thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT gasperinic thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT sastregarrigaj thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT evangeloun thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT palacej thecurrentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT geraldesr currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT ciccarellio currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT barkhoff currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT destefanon currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT enzingerc currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT filippim currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT hoferm currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT paulf currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT preziosap currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT roviraa currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT delucag currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT kapposl currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT yousryt currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT fazekasf currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT frederiksenj currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT gasperinic currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT sastregarrigaj currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT evangeloun currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics AT palacej currentroleofmriindifferentiatingmultiplesclerosisfromitsimagingmimics |