A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip.
OBJECTIVES: Osteoarthritis (OA) is the most common form of arthritis with a clear genetic component. To identify novel loci associated with hip OA we performed a meta-analysis of genome-wide association studies (GWAS) on European subjects. METHODS: We performed a two-stage meta-analysis on more than...
Main Authors: | Evangelou, E, Kerkhof, H, Styrkarsdottir, U, Ntzani, E, Bos, S, Esko, T, Evans, D, Metrustry, S, Panoutsopoulou, K, Ramos, Y, Thorleifsson, G, Tsilidis, K, Arden, N, Aslam, N, Bellamy, N, Birrell, F, Blanco, F, Carr, A, Chapman, K, Day-Williams, A, Deloukas, P, Doherty, M, Engström, G, Helgadottir, H, Hofman, A |
---|---|
格式: | Journal article |
语言: | English |
出版: |
2014
|
相似书籍
-
Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies.
由: Rodriguez-Fontenla, C, et al.
出版: (2014) -
A variant in MCF2L is associated with osteoarthritis.
由: Day-Williams, A, et al.
出版: (2011) -
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22.
由: Evangelou, E, et al.
出版: (2011) -
Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31.
由: Styrkarsdottir, U, et al.
出版: (2014) -
COMMON VARIANTS IN SKELETAL DYSPLASIA GENES ARE ASSOCIATED WITH OSTEOARTHRITIS
由: Kerkhof, H, et al.
出版: (2011)