DOCK8 is essential for T-cell survival and the maintenance of CD8 + T-cell memory

DOCK8 is essential for T-cell survival and the maintenance of CD8 + T-cell memory

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Deficiency in the guanine nucleotide exchange factor dedicator of cytokinesis 8 (DOCK8) causes a human immunodeficiency syndrome associated with recurrent sinopulmonary and viral infections. We have recently identified a DOCK8-deficient mouse strain, carrying an ethylnitrosourea-induced splice-site...

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Bibliographic Details
Main Authors:	Lambe, T, Crawford, G, Johnson, A, Crockford, T, Bouriez-Jones, T, Smyth, A, Pham, T, Zhang, Q, Freeman, A, Cyster, J, Su, H, Cornall, R
Format:	Journal article
Language:	English
Published:	2011

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