Classical pathway complement destruction is not responsible for the loss of human erythrocytes during porcine liver perfusion.

BACKGROUND: Porcine livers perfused with human blood destroy 85% of human erythrocytes (red blood cells [RBC]) during prolonged extracorporeal perfusion, raising the possibility of a complement-mediated graft-versus-host effect. METHODS: Isolated porcine livers were perfused with fresh human blood....

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Bibliographic Details
Main Authors: Rees, M, Butler, A, Negus, M, Davies, H, Friend, P
Format: Journal article
Language:English
Published: 2004