Nerve growth factor-induced PKB/Akt activity is sustained by phosphoinositide 3-kinase dependent and independent signals in sympathetic neurons.
Phosphoinositide 3-kinase and its downstream effector kinase PKB/Akt have been suggested to have crucial roles in suppressing apoptosis in several classes of neurons. However, few studies have conducted a long-term investigation of either kinase activity, many studies relying instead on use of the p...
প্রধান লেখক: | Virdee, K, Xue, L, Hemmings, B, Goemans, C, Heumann, R, Tolkovsky, A |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
1999
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