Interactions of pleckstrin homology domains with membranes: adding back the bilayer via high throughput molecular dynamics

Interactions of pleckstrin homology domains with membranes: adding back the bilayer via high throughput molecular dynamics

In this study we present a multi-scale molecular simulation pipeline for determining the favoured mode of interaction of a pleckstrin homology (PH) domain with a phosphatidyl-inositol-phosphate (PIP)-containing lipid bilayer. This allows us to predict PH/membrane interactions across a number of PH d...

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Bibliographic Details
Main Authors:	Yamamoto, E, Kalli, A, Yasuoka, K, Sansom, M
Format:	Journal article
Published:	Cell Press 2016

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