Interactions of pleckstrin homology domains with membranes: adding back the bilayer via high throughput molecular dynamics

In this study we present a multi-scale molecular simulation pipeline for determining the favoured mode of interaction of a pleckstrin homology (PH) domain with a phosphatidyl-inositol-phosphate (PIP)-containing lipid bilayer. This allows us to predict PH/membrane interactions across a number of PH d...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Yamamoto, E, Kalli, A, Yasuoka, K, Sansom, M
Fformat: Journal article
Cyhoeddwyd: Cell Press 2016