Inhibition of UDP-Gal mutase and mycobacterial galactan biosynthesis by pyrrolidine analogues of galactofuranose

Inhibition of UDP-Gal mutase and mycobacterial galactan biosynthesis by pyrrolidine analogues of galactofuranose

Some pyrrolidine analogues of galactofuranose - synthesised from carbohydrate lactones - are the first known inhibitors of E. coli K12 UDP-Gal mutase and mycobacterial galactan biosynthesis. This inhibition may form chemotherapeutic strategy for the treatment of human pathogens which contain integra...

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Bibliographic Details
Main Authors:	Lee, R, Smith, M, Nash, R, Griffiths, R, McNeil, M, Grewal, R, Yan, W, Besra, G, Brennan, P, Fleet, G
Format:	Journal article
Published:	1997

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