Optimising CRISPR for targeting of primary haematopoietic stem cells

Optimising CRISPR for targeting of primary haematopoietic stem cells

<p>CRISPR (clustered regularly interspaced short palindromic repeats) offers an unprecedented array of genetic tools for treating and modelling haematological disorders. However, there are concerns about its safety. CRISPR-based editing can induce upregulation of TP53 associated pathways, a f...

書目詳細資料
主要作者:	Field, L
其他作者:	Mead, A
格式:	Thesis
語言:	English
出版:	2021
主題:	Molecular biology

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