Optimising CRISPR for targeting of primary haematopoietic stem cells

Optimising CRISPR for targeting of primary haematopoietic stem cells

<p>CRISPR (clustered regularly interspaced short palindromic repeats) offers an unprecedented array of genetic tools for treating and modelling haematological disorders. However, there are concerns about its safety. CRISPR-based editing can induce upregulation of TP53 associated pathways, a f...

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Dades bibliogràfiques
Autor principal:	Field, L
Altres autors:	Mead, A
Format:	Thesis
Idioma:	English
Publicat:	2021
Matèries:	Molecular biology

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