Optimising CRISPR for targeting of primary haematopoietic stem cells

Optimising CRISPR for targeting of primary haematopoietic stem cells

<p>CRISPR (clustered regularly interspaced short palindromic repeats) offers an unprecedented array of genetic tools for treating and modelling haematological disorders. However, there are concerns about its safety. CRISPR-based editing can induce upregulation of TP53 associated pathways, a f...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoir:	Field, L
Rannpháirtithe:	Mead, A
Formáid:	Tráchtas
Teanga:	English
Foilsithe / Cruthaithe:	2021
Ábhair:	Molecular biology

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