Optimising CRISPR for targeting of primary haematopoietic stem cells

<p>CRISPR (clustered regularly interspaced short palindromic repeats) offers an unprecedented array of genetic tools for treating and modelling haematological disorders. However, there are concerns about its safety. CRISPR-based editing can induce upregulation of TP53 associated pathways, a f...

Ausführliche Beschreibung

Bibliographische Detailangaben
1. Verfasser: Field, L
Weitere Verfasser: Mead, A
Format: Abschlussarbeit
Sprache:English
Veröffentlicht: 2021
Schlagworte: