Optimising CRISPR for targeting of primary haematopoietic stem cells
<p>CRISPR (clustered regularly interspaced short palindromic repeats) offers an unprecedented array of genetic tools for treating and modelling haematological disorders. However, there are concerns about its safety. CRISPR-based editing can induce upregulation of TP53 associated pathways, a f...
Huvudupphovsman: | |
---|---|
Övriga upphovsmän: | |
Materialtyp: | Lärdomsprov |
Språk: | English |
Publicerad: |
2021
|
Ämnen: |