Optimising CRISPR for targeting of primary haematopoietic stem cells

<p>CRISPR (clustered regularly interspaced short palindromic repeats) offers an unprecedented array of genetic tools for treating and modelling haematological disorders. However, there are concerns about its safety. CRISPR-based editing can induce upregulation of TP53 associated pathways, a f...

Повний опис

Бібліографічні деталі
Автор: Field, L
Інші автори: Mead, A
Формат: Дисертація
Мова:English
Опубліковано: 2021
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