Optimising CRISPR for targeting of primary haematopoietic stem cells
<p>CRISPR (clustered regularly interspaced short palindromic repeats) offers an unprecedented array of genetic tools for treating and modelling haematological disorders. However, there are concerns about its safety. CRISPR-based editing can induce upregulation of TP53 associated pathways, a f...
Tác giả chính: | |
---|---|
Tác giả khác: | |
Định dạng: | Luận văn |
Ngôn ngữ: | English |
Được phát hành: |
2021
|
Những chủ đề: |