Exceptionally slow kinetics of the intramolecular quadruplex formed by the Oxytricha telomeric repeat.

We examined the stability and kinetics of folding of the Oxytricha telomeric repeat sequence (G4T4)4. Fluorescence melting experiments show that this intramolecular quadruplex, which is more stable in potassium- than sodium-containing buffers, shows considerable hysteresis between the melting and an...

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Main Authors: Brown, N, Rachwal, P, Brown, T, Fox, K
פורמט: Journal article
שפה:English
יצא לאור: 2005