Combining statistical alignment and phylogenetic footprinting to detect regulatory elements.

MOTIVATION: Traditional alignment-based phylogenetic footprinting approaches make predictions on the basis of a single assumed alignment. The predictions are therefore highly sensitive to alignment errors or regions of alignment uncertainty. Alternatively, statistical alignment methods provide a fr...

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Bibliographic Details
Main Authors: Satija, R, Pachter, L, Hein, J
Format: Journal article
Language:English
Published: 2008

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