Diversification of colonization factors in a multidrug-resistant escherichia coli lineage evolving under negative frequency-dependent selection

Escherichia coli is a major cause of bloodstream and urinary tract infections globally. The wide dissemination of multidrug-resistant (MDR) strains of extraintestinal pathogenic E. coli (ExPEC) poses a rapidly increasing public health burden due to narrowed treatment options and increased risk of fa...

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Main Authors: McNally, A, Kallonen, T, Connor, C, Abudahab, K, Aanensen, D, Horner, C, Peacock, S, Parkhill, J, Croucher, N, Corander, J
格式: Journal article
語言:English
出版: American Society for Microbiology 2019