The cost and benefit of quorum sensing‐controlled bacteriocin production in Lactobacillus plantarum
Bacteria eliminate competitors via ‘chemical warfare’ with bacteriocins. Some species appear to adjust bacteriocin production conditionally in response to the social environment. We tested whether variation in the cost and benefit of producing bacteriocins could explain such conditional behaviour, i...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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Wiley
2019
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| _version_ | 1826297862178209792 |
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| author | Maldonado-Barragán, A West, SA |
| author_facet | Maldonado-Barragán, A West, SA |
| author_sort | Maldonado-Barragán, A |
| collection | OXFORD |
| description | Bacteria eliminate competitors via ‘chemical warfare’ with bacteriocins. Some species appear to adjust bacteriocin production conditionally in response to the social environment. We tested whether variation in the cost and benefit of producing bacteriocins could explain such conditional behaviour, in the bacteria Lactobacillus plantarum. We found that: (a) bacterial bacteriocin production could be upregulated by either the addition of a synthetic autoinducer peptide (PLNC8IF; signalling molecule), or by a plasmid which constitutively encodes for the production of this peptide; (b) bacteriocin production is costly, leading to reduced growth when grown in poor and, to a lesser extent, in rich media; (c) bacteriocin production provides a fitness advantage, when grown in competition with sensitive strains; and (d) the fitness benefits provided by bacteriocin production are greater at higher cell densities. These results show how the costs and benefits of upregulating bacteriocin production can depend upon abiotic and biotic conditions. |
| first_indexed | 2024-03-07T04:38:05Z |
| format | Journal article |
| id | oxford-uuid:d0aad196-f9a0-4e48-b289-790be158eb7f |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:38:05Z |
| publishDate | 2019 |
| publisher | Wiley |
| record_format | dspace |
| spelling | oxford-uuid:d0aad196-f9a0-4e48-b289-790be158eb7f2022-03-27T07:51:38ZThe cost and benefit of quorum sensing‐controlled bacteriocin production in Lactobacillus plantarumJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d0aad196-f9a0-4e48-b289-790be158eb7fEnglishSymplectic ElementsWiley2019Maldonado-Barragán, AWest, SABacteria eliminate competitors via ‘chemical warfare’ with bacteriocins. Some species appear to adjust bacteriocin production conditionally in response to the social environment. We tested whether variation in the cost and benefit of producing bacteriocins could explain such conditional behaviour, in the bacteria Lactobacillus plantarum. We found that: (a) bacterial bacteriocin production could be upregulated by either the addition of a synthetic autoinducer peptide (PLNC8IF; signalling molecule), or by a plasmid which constitutively encodes for the production of this peptide; (b) bacteriocin production is costly, leading to reduced growth when grown in poor and, to a lesser extent, in rich media; (c) bacteriocin production provides a fitness advantage, when grown in competition with sensitive strains; and (d) the fitness benefits provided by bacteriocin production are greater at higher cell densities. These results show how the costs and benefits of upregulating bacteriocin production can depend upon abiotic and biotic conditions. |
| spellingShingle | Maldonado-Barragán, A West, SA The cost and benefit of quorum sensing‐controlled bacteriocin production in Lactobacillus plantarum |
| title | The cost and benefit of quorum sensing‐controlled bacteriocin production in Lactobacillus plantarum |
| title_full | The cost and benefit of quorum sensing‐controlled bacteriocin production in Lactobacillus plantarum |
| title_fullStr | The cost and benefit of quorum sensing‐controlled bacteriocin production in Lactobacillus plantarum |
| title_full_unstemmed | The cost and benefit of quorum sensing‐controlled bacteriocin production in Lactobacillus plantarum |
| title_short | The cost and benefit of quorum sensing‐controlled bacteriocin production in Lactobacillus plantarum |
| title_sort | cost and benefit of quorum sensing controlled bacteriocin production in lactobacillus plantarum |
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