Crystal structure of a human GABAA receptor

Type-A γ-aminobutyric acid receptors (GABAA Rs) are the principal mediators of rapid inhibitory synaptic transmission in the human brain. A decline in GABAA R signalling triggers hyperactive neurological disorders such as insomnia, anxiety and epilepsy. Here we present the first three-dimensional st...

詳細記述

書誌詳細
主要な著者: Miller, P, Aricescu, A
フォーマット: Journal article
言語:English
出版事項: Nature Publishing Group 2014