Campath-1G in vivo confers a low incidence of graft-versus-host disease associated with a high incidence of mixed chimaerism after bone marrow transplantation for severe aplastic anaemia using HLA-identical sibling donors.

We have evaluated the effect of in vivo Campath-1G on engraftment and GVHD in 23 patients with severe aplastic anaemia transplanted from HLA-identical sibling donors. In 14 patients Campath 1g was given pre-transplant for up to 9 days in an attempt to overcome graft rejection (group 1). In nine pati...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Hamblin, M, Marsh, J, Lawler, M, McCann, SR, Wickham, N, Dunlop, L, Ball, S, Davies, E, Hale, G, Waldmann, H, Gordon-Smith, E
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 1996