Age-related increase in levels of 5-hydroxymethylcytosine in mouse hippocampus is prevented by caloric restriction.

Aberrations in epigenetic marks have been associated with aging of the brain while caloric restriction (CR) and upregulation of endogenous antioxidants have been suggested as tools to attenuate the aging process. We have recently observed age-related increases in levels of 5-methylcytidine (5-mC) an...

詳細記述

書誌詳細
主要な著者: Chouliaras, L, van den Hove, D, Kenis, G, Keitel, S, Hof, P, van Os, J, Steinbusch, H, Schmitz, C, Rutten, B
フォーマット: Journal article
言語:English
出版事項: 2012