The role of the Xist 5' m6A region and RBM15 in X chromosome inactivation
<strong>Background:</strong> X chromosome inactivation in mammals is regulated by the non-coding (nc) RNA, Xist, which represses the chromosome from which it is transcribed. High levels of the N6-methyladenosine (m6A) RNA modification occur within Xist exon I, close to the 5’ end of the...
Main Authors: | Coker, H, Wei, G, Moindrot, B, Mohammed, S, Nesterova, T, Brockdorff, N |
---|---|
Format: | Journal article |
Language: | English |
Published: |
F1000Research
2020
|
Similar Items
-
A pooled shRNA screen identifies Rbm15, Spen, and Wtap as factors required for Xist RNA-mediated silencing
by: Moindrot, B, et al.
Published: (2015) -
Disruption of a conserved region of Xist exon 1 impairs Xist RNA localisation and X-linked gene silencing during random and imprinted X chromosome inactivation.
by: Senner, C, et al.
Published: (2011) -
Variability of sequence surrounding the Xist gene in rodents suggests taxon-specific regulation of X chromosome inactivation.
by: Shevchenko, A, et al.
Published: (2011) -
Xist gene regulation at the onset of X inactivation.
by: Senner, C, et al.
Published: (2009) -
Xist Repeats B and C, but not Repeat A, mediate de novo recruitment of the Polycomb system in X chromosome inactivation
by: Wei, G, et al.
Published: (2021)