NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells.

NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells.

Modification in the function of dendritic cells (DC), such as that achieved by microbial stimuli or T cell help, plays a critical role in determining the quality and size of adaptive responses to Ag. NKT cells bearing an invariant TCR (iNKT cells) restricted by nonpolymorphic CD1d molecules may cons...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	Hermans, I, Silk, J, Gileadi, U, Salio, M, Mathew, B, Ritter, G, Schmidt, R, Harris, A, Old, L, Cerundolo, V
Format:	Journal article
Sprog:	English
Udgivet:	2003

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