NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells.

NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells.

Modification in the function of dendritic cells (DC), such as that achieved by microbial stimuli or T cell help, plays a critical role in determining the quality and size of adaptive responses to Ag. NKT cells bearing an invariant TCR (iNKT cells) restricted by nonpolymorphic CD1d molecules may cons...

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Detalles Bibliográficos
Main Authors: Hermans, I, Silk, J, Gileadi, U, Salio, M, Mathew, B, Ritter, G, Schmidt, R, Harris, A, Old, L, Cerundolo, V
Formato: Journal article
Idioma:English
Publicado: 2003

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