NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells.

NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells.

Modification in the function of dendritic cells (DC), such as that achieved by microbial stimuli or T cell help, plays a critical role in determining the quality and size of adaptive responses to Ag. NKT cells bearing an invariant TCR (iNKT cells) restricted by nonpolymorphic CD1d molecules may cons...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Hermans, I, Silk, J, Gileadi, U, Salio, M, Mathew, B, Ritter, G, Schmidt, R, Harris, A, Old, L, Cerundolo, V
Natura:	Journal article
Lingua:	English
Pubblicazione:	2003

Documenti analoghi

Dendritic cell function can be modulated through cooperative actions of TLR ligands and invariant NKT cells.
di: Hermans, I, et al.
Pubblicazione: (2007)

Nonglycosidic CD1d lipid ligands activate human and murine invariant NKT cells
di: Silk, J, et al.
Pubblicazione: (2008)

CpG-matured murine plasmacytoid dendritic cells are capable of in vivo priming of functional CD8 T cell responses to endogenous but not exogenous antigens.
di: Salio, M, et al.
Pubblicazione: (2004)

Cutting edge: nonglycosidic CD1d lipid ligands activate human and murine invariant NKT cells.
di: Silk, J, et al.
Pubblicazione: (2008)

Harnessing invariant NKT cells in vaccination strategies.
di: Cerundolo, V, et al.
Pubblicazione: (2009)

Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell-mediated immunotherapy
di: Silk, J, et al.
Pubblicazione: (2004)

Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell-mediated immunotherapy.
di: Silk, J, et al.
Pubblicazione: (2004)

Nonglycosidic agonists of invariant NKT cells for use as vaccine adjuvants.
di: Reddy, BG, et al.
Pubblicazione: (2009)

B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo.
di: Barral, P, et al.
Pubblicazione: (2008)

A closer look at CD1d molecules: new horizons in studying NKT cells.
di: Stronge, V, et al.
Pubblicazione: (2007)

The actin cytoskeleton modulates the activation of invariant NKT cells by segregating CD1d nanoclusters on antigen presenting cells
di: Cerundolo, V, et al.
Pubblicazione: (2016)

Harnessing NKT cells for therapeutic applications.
di: Cerundolo, V, et al.
Pubblicazione: (2007)

Exploiting the role of endogenous lymphoid-resident dendritic cells in the priming of NKT cells and CD8+ T cells to dendritic cell-based vaccines.
di: Troels R Petersen, et al.
Pubblicazione: (2011-03-01)

Recent advances in processing and presentation of CD1 bound lipid antigens.
di: Salio, M, et al.
Pubblicazione: (2010)

Biology of CD1- and MR1-restricted T cells.
di: Salio, M, et al.
Pubblicazione: (2014)

Increasing the survival of dendritic cells in vivo does not replace the requirement for CD4+ T cell help during primary CD8+ T cell responses.
di: Matthews, K, et al.
Pubblicazione: (2007)

Mature dendritic cells differentiated in the presence of interferon-beta and interleukin-3 prime functional antigen-specific CD8 T cells.
di: Renneson, J, et al.
Pubblicazione: (2005)

Invariant NKT Cell at the Interface between Innate and Adaptive Immunity
di: Salio, M, et al.
Pubblicazione: (2011)

The VITAL assay: a versatile fluorometric technique for assessing CTL- and NKT-mediated cytotoxicity against multiple targets in vitro and in vivo.
di: Hermans, I, et al.
Pubblicazione: (2004)

Regulation of hematopoiesis in vitro and in vivo by invariant NKT cells.
di: Kotsianidis, I, et al.
Pubblicazione: (2006)

Immunization with a lentivector that targets tumor antigen expression to dendritic cells induces potent CD8+ and CD4+ T-cell responses.
di: Lopes, L, et al.
Pubblicazione: (2008)

The length of lipids bound to human CD1d molecules modulates the affinity of NKT cell TCR and the threshold of NKT cell activation.
di: McCarthy, C, et al.
Pubblicazione: (2007)

Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141 XCR1 dendritic cells
di: Silk, K, et al.
Pubblicazione: (2012)

Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
di: Silk, K, et al.
Pubblicazione: (2012)

Regulation of hematopoiesis in vitro and in vivo by invariant NKT cells.
di: Kotsianidis, I, et al.
Pubblicazione: (2005)

Dendritic cells: a journey from laboratory to clinic.
di: Cerundolo, V, et al.
Pubblicazione: (2004)

Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+ T cell tolerance in vivo.
di: Luckashenak, N, et al.
Pubblicazione: (2008)

The role of invariant NKT cells in enhancing antigen specific T and B cell responses
di: Cerundolo, V
Pubblicazione: (2005)

CD169(+) macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes.
di: Barral, P, et al.
Pubblicazione: (2010)

Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells.
di: Porubsky, S, et al.
Pubblicazione: (2012)

Activation of human mucosal-associated invariant T cells induces CD40L-dependent maturation of monocyte-derived and primary dendritic cells
di: Salio, M, et al.
Pubblicazione: (2018)

Harnessing invariant NKT-cells to enhance antigen specific immune responses
di: Cerundolo, V
Pubblicazione: (2014)

CD8+ T-cell immunity orchestrated by iNKT cells
di: Yingyu Qin, et al.
Pubblicazione: (2023-01-01)

Diverse endogenous antigens for mouse NKT cells: self-antigens that are not glycosphingolipids.
di: Pei, B, et al.
Pubblicazione: (2011)

CD8(+) T cells mediate CD40-independent maturation of dendritic cells in vivo.
di: Ruedl, C, et al.
Pubblicazione: (1999)

CTL priming by CD8(+) and CD8(-) dendritic cells in vivo.
di: Ruedl, C, et al.
Pubblicazione: (1999)

IL-7 During Antigenic Stimulation Using Allogeneic Dendritic Cells Promotes Expansion of CD45RA-CD62L+CD4+ Invariant NKT Cells With Th-2 Biased Cytokine Production Profile
di: Abel Trujillo-Ocampo, et al.
Pubblicazione: (2020-11-01)

Induction of CD4+ T-cell responses by dendritic cells in vivo
di: Suri, R, et al.
Pubblicazione: (1998)

B Cell Help by CD1d-Rectricted NKT Cells
di: Livia Clerici, et al.
Pubblicazione: (2015-10-01)

CD4(-)CD8alphaalpha subset of CD1d-restricted NKT cells controls T cell expansion.
di: Ho, L, et al.
Pubblicazione: (2004)