NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells.
Modification in the function of dendritic cells (DC), such as that achieved by microbial stimuli or T cell help, plays a critical role in determining the quality and size of adaptive responses to Ag. NKT cells bearing an invariant TCR (iNKT cells) restricted by nonpolymorphic CD1d molecules may cons...
Main Authors: | Hermans, I, Silk, J, Gileadi, U, Salio, M, Mathew, B, Ritter, G, Schmidt, R, Harris, A, Old, L, Cerundolo, V |
---|---|
Format: | Journal article |
Jezik: | English |
Izdano: |
2003
|
Podobne knjige/članki
-
Dendritic cell function can be modulated through cooperative actions of TLR ligands and invariant NKT cells.
od: Hermans, I, et al.
Izdano: (2007) -
CpG-matured murine plasmacytoid dendritic cells are capable of in vivo priming of functional CD8 T cell responses to endogenous but not exogenous antigens.
od: Salio, M, et al.
Izdano: (2004) -
Nonglycosidic CD1d lipid ligands activate human and murine invariant NKT cells
od: Silk, J, et al.
Izdano: (2008) -
Cutting edge: nonglycosidic CD1d lipid ligands activate human and murine invariant NKT cells.
od: Silk, J, et al.
Izdano: (2008) -
Harnessing invariant NKT cells in vaccination strategies.
od: Cerundolo, V, et al.
Izdano: (2009)