Application of cardiac electrophysiology simulations to pro-arrhythmic safety testing.
Concerns over cardiac side effects are the largest single cause of compound attrition during pharmaceutical drug development. For a number of years, biophysically detailed mathematical models of cardiac electrical activity have been used to explore how a compound, interfering with specific ion-chann...
| Prif Awduron: | , , , , |
|---|---|
| Fformat: | Journal article |
| Iaith: | English |
| Cyhoeddwyd: |
2012
|
Search Result 1
Application of cardiac electrophysiology simulations to pro−arrhythmic safety testing
Cyhoeddwyd 2012
Journal article