Gestational vitamin D supplementation leads to reduced perinatal RXRA DNA methylation: results from the MAVIDOS trial

Gestational vitamin D supplementation leads to reduced perinatal RXRA DNA methylation: results from the MAVIDOS trial

We have previously demonstrated inverse associations between maternal 25(OH)-vitamin D status and perinatal DNA methylation at the retinoid-X-receptor-alpha (RXRA) locus and between RXRA methylation and offspring bone mass. In this study, we used an existing randomized trial to test the hypothesis t...

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Dades bibliogràfiques
Autors principals: Curtis, EM, Krstic, N, Cook, E, D'Angelo, S, Crozier, SR, Moon, RJ, Murray, R, Garratt, E, Costello, P, Cleal, J, Ashley, B, Bishop, NJ, Kennedy, S, Papageorghiou, AT, Schoenmakers, I, Fraser, R, Gandhi, SV, Prentice, A, Javaid, MK, Inskip, HM, Godfrey, KM, Bell, CG, Lillycrop, KA, Cooper, C, Harvey, NC, Mavidos Trial Group
Format: Journal article
Idioma:English
Publicat: Wiley 2018

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