A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability.

A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability.

FANCM remodels branched DNA structures and plays essential roles in the cellular response to DNA replication stress. Here, we show that FANCM forms a conserved DNA-remodeling complex with a histone-fold heterodimer, MHF. We find that MHF stimulates DNA binding and replication fork remodeling by FANC...

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Bibliographic Details
Main Authors: Yan, Z, Delannoy, M, Ling, C, Daee, D, Osman, F, Muniandy, P, Shen, X, Oostra, AB, Du, H, Steltenpool, J, Lin, T, Schuster, B, Décaillet, C, Stasiak, A, Stone, S, Hoatlin, M, Schindler, D, Woodcock, C, Joenje, H, Sen, R, de Winter, J, Li, L, Seidman, M, Whitby, M
Format: Journal article
Language:English
Published: 2010

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