RH5.1-CyRPA-Ripr antigen combination vaccine shows little improvement over RH5.1 in a preclinical setting

RH5.1-CyRPA-Ripr antigen combination vaccine shows little improvement over RH5.1 in a preclinical setting

<strong>Background: </strong>RH5 is the leading vaccine candidate for the Plasmodium falciparum blood stage and has shown impact on parasite growth in the blood in a human clinical trial. RH5 binds to Ripr and CyRPA at the apical end of the invasive merozoite form, and this complex, desi...

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Автори: Healer, J, Thompson, JK, Mackwell, KL, Browne, CD, Seager, BA, Ngo, A, Lowes, KN, Silk, SE, Pulido, D, King, LDW, Christen, JM, Noe, AR, Kotraiah, V, Masendycz, PJ, Rajagopalan, R, Lucas, L, Stanford, MM, Soisson, L, Diggs, C, Miller, R, Youll, S, Wycherley, K, Draper, SJ, Cowman, AF
Формат: Journal article
Мова:English
Опубліковано: Frontiers Media 2022

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