Biological activity, membrane-targeting modification, and crystallization of soluble human decay accelerating factor expressed in E. coli.

Biological activity, membrane-targeting modification, and crystallization of soluble human decay accelerating factor expressed in E. coli.

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Decay-accelerating factor (DAF, CD55) is a glycophosphatidyl inositol-anchored glycoprotein that regulates the activity of C3 and C5 convertases. In addition to understanding the mechanism of complement inhibition by DAF through structural studies, there is also an interest in the possible therapeut...

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Detalles Bibliográficos
Main Authors: White, J, Lukacik, P, Esser, D, Steward, M, Giddings, N, Bright, JR, Fritchley, S, Morgan, B, Lea, S, Smith, G, Smith, R
Formato: Journal article
Idioma:English
Publicado: 2004

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