Foot-and-mouth disease virus can induce a specific and rapid CD4+ T-cell-independent neutralizing and isotype class-switched antibody response in naive cattle.

Foot-and-mouth disease virus can induce a specific and rapid CD4+ T-cell-independent neutralizing and isotype class-switched antibody response in naive cattle.

The role of T-lymphocyte subsets in recovery from foot-and-mouth disease virus (FMDV) infection in calves was investigated by administering subset-specific monoclonal antibodies. The depletion of circulating CD4(+) or WC1(+) gammadelta T cells was achieved for a period extending from before challeng...

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Bibliographic Details
Main Authors:	Juleff, N, Windsor, M, Lefevre, E, Gubbins, S, Hamblin, P, Reid, E, McLaughlin, K, Beverley, P, Morrison, I, Charleston, B
Format:	Journal article
Language:	English
Published:	2009

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