Highly chemo- and stereoselective intermolecular coupling of diazoacetates to give cis-olefins by using Grubbs second-generation catalyst.
Highly stereoselective formation of cis-2-ene-1,4-diesters by homo- and heterocoupling of alpha-diazoacetates in the presence of Grubbs second-generation catalyst is demonstrated. The dual reactivity of the catalyst in alkene metathesis and diazocoupling has been exploited in the synthesis of 12-26-...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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2007
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| _version_ | 1797096411889664000 |
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| author | Hodgson, D Angrish, D |
| author_facet | Hodgson, D Angrish, D |
| author_sort | Hodgson, D |
| collection | OXFORD |
| description | Highly stereoselective formation of cis-2-ene-1,4-diesters by homo- and heterocoupling of alpha-diazoacetates in the presence of Grubbs second-generation catalyst is demonstrated. The dual reactivity of the catalyst in alkene metathesis and diazocoupling has been exploited in the synthesis of 12-26-membered macrocyclic dienyl dilactones by one-pot carbene dimerisation/ring-closing metathesis. |
| first_indexed | 2024-03-07T04:41:28Z |
| format | Journal article |
| id | oxford-uuid:d1cd4c87-5b60-4cf6-b029-f3fb18908af5 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:41:28Z |
| publishDate | 2007 |
| record_format | dspace |
| spelling | oxford-uuid:d1cd4c87-5b60-4cf6-b029-f3fb18908af52022-03-27T07:59:23ZHighly chemo- and stereoselective intermolecular coupling of diazoacetates to give cis-olefins by using Grubbs second-generation catalyst.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d1cd4c87-5b60-4cf6-b029-f3fb18908af5EnglishSymplectic Elements at Oxford2007Hodgson, DAngrish, DHighly stereoselective formation of cis-2-ene-1,4-diesters by homo- and heterocoupling of alpha-diazoacetates in the presence of Grubbs second-generation catalyst is demonstrated. The dual reactivity of the catalyst in alkene metathesis and diazocoupling has been exploited in the synthesis of 12-26-membered macrocyclic dienyl dilactones by one-pot carbene dimerisation/ring-closing metathesis. |
| spellingShingle | Hodgson, D Angrish, D Highly chemo- and stereoselective intermolecular coupling of diazoacetates to give cis-olefins by using Grubbs second-generation catalyst. |
| title | Highly chemo- and stereoselective intermolecular coupling of diazoacetates to give cis-olefins by using Grubbs second-generation catalyst. |
| title_full | Highly chemo- and stereoselective intermolecular coupling of diazoacetates to give cis-olefins by using Grubbs second-generation catalyst. |
| title_fullStr | Highly chemo- and stereoselective intermolecular coupling of diazoacetates to give cis-olefins by using Grubbs second-generation catalyst. |
| title_full_unstemmed | Highly chemo- and stereoselective intermolecular coupling of diazoacetates to give cis-olefins by using Grubbs second-generation catalyst. |
| title_short | Highly chemo- and stereoselective intermolecular coupling of diazoacetates to give cis-olefins by using Grubbs second-generation catalyst. |
| title_sort | highly chemo and stereoselective intermolecular coupling of diazoacetates to give cis olefins by using grubbs second generation catalyst |
| work_keys_str_mv | AT hodgsond highlychemoandstereoselectiveintermolecularcouplingofdiazoacetatestogivecisolefinsbyusinggrubbssecondgenerationcatalyst AT angrishd highlychemoandstereoselectiveintermolecularcouplingofdiazoacetatestogivecisolefinsbyusinggrubbssecondgenerationcatalyst |