Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae

<p style="text-align:justify;"> Gonorrhoea infections are on the increase and strains that are resistant to all antimicrobials used to treat the disease have been found worldwide. These observations encouraged the World Health Organization to include Neisseria gonorrhoeae on their l...

詳細記述

書誌詳細
主要な著者: Sanchez-Buso, L, Harris, SR
フォーマット: Journal article
言語:English
出版事項: Microbiology Society 2019
その他の書誌記述
要約:<p style="text-align:justify;"> Gonorrhoea infections are on the increase and strains that are resistant to all antimicrobials used to treat the disease have been found worldwide. These observations encouraged the World Health Organization to include Neisseria gonorrhoeae on their list of high-priority organisms in need of new treatments. Fortunately, concurrent resistance to both antimicrobials used in dual therapy is still rare. The fight against antimicrobial resistance (AMR) must begin from an understanding of how it evolves and spreads in sexual networks. Genome-based analyses have allowed the study of the gonococcal population dynamics and transmission, giving a novel perspective on AMR gonorrhoea. Here, we will review past, present and future treatment options for gonorrhoea and explain how genomics is helping to increase our understanding of the changing AMR and transmission landscape. This article contains data hosted by <a href="https://microreact.org/project/rJQ6FGj8G" target="_blank">Microreact</a>. </p>