Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae
<p style="text-align:justify;"> Gonorrhoea infections are on the increase and strains that are resistant to all antimicrobials used to treat the disease have been found worldwide. These observations encouraged the World Health Organization to include Neisseria gonorrhoeae on their l...
मुख्य लेखकों: | , |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
Microbiology Society
2019
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_version_ | 1826298164634714112 |
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author | Sanchez-Buso, L Harris, SR |
author_facet | Sanchez-Buso, L Harris, SR |
author_sort | Sanchez-Buso, L |
collection | OXFORD |
description | <p style="text-align:justify;"> Gonorrhoea infections are on the increase and strains that are resistant to all antimicrobials used to treat the disease have been found worldwide. These observations encouraged the World Health Organization to include Neisseria gonorrhoeae on their list of high-priority organisms in need of new treatments. Fortunately, concurrent resistance to both antimicrobials used in dual therapy is still rare. The fight against antimicrobial resistance (AMR) must begin from an understanding of how it evolves and spreads in sexual networks. Genome-based analyses have allowed the study of the gonococcal population dynamics and transmission, giving a novel perspective on AMR gonorrhoea. Here, we will review past, present and future treatment options for gonorrhoea and explain how genomics is helping to increase our understanding of the changing AMR and transmission landscape. This article contains data hosted by <a href="https://microreact.org/project/rJQ6FGj8G" target="_blank">Microreact</a>. </p> |
first_indexed | 2024-03-07T04:42:41Z |
format | Journal article |
id | oxford-uuid:d22fe6c3-b718-4b5e-b775-24af39f5851b |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T04:42:41Z |
publishDate | 2019 |
publisher | Microbiology Society |
record_format | dspace |
spelling | oxford-uuid:d22fe6c3-b718-4b5e-b775-24af39f5851b2022-03-27T08:02:09ZUsing genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeaeJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d22fe6c3-b718-4b5e-b775-24af39f5851bEnglishSymplectic Elements at OxfordMicrobiology Society2019Sanchez-Buso, LHarris, SR <p style="text-align:justify;"> Gonorrhoea infections are on the increase and strains that are resistant to all antimicrobials used to treat the disease have been found worldwide. These observations encouraged the World Health Organization to include Neisseria gonorrhoeae on their list of high-priority organisms in need of new treatments. Fortunately, concurrent resistance to both antimicrobials used in dual therapy is still rare. The fight against antimicrobial resistance (AMR) must begin from an understanding of how it evolves and spreads in sexual networks. Genome-based analyses have allowed the study of the gonococcal population dynamics and transmission, giving a novel perspective on AMR gonorrhoea. Here, we will review past, present and future treatment options for gonorrhoea and explain how genomics is helping to increase our understanding of the changing AMR and transmission landscape. This article contains data hosted by <a href="https://microreact.org/project/rJQ6FGj8G" target="_blank">Microreact</a>. </p> |
spellingShingle | Sanchez-Buso, L Harris, SR Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae |
title | Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae |
title_full | Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae |
title_fullStr | Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae |
title_full_unstemmed | Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae |
title_short | Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae |
title_sort | using genomics to understand antimicrobial resistance and transmission in neisseria gonorrhoeae |
work_keys_str_mv | AT sanchezbusol usinggenomicstounderstandantimicrobialresistanceandtransmissioninneisseriagonorrhoeae AT harrissr usinggenomicstounderstandantimicrobialresistanceandtransmissioninneisseriagonorrhoeae |