Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae

<p style="text-align:justify;"> Gonorrhoea infections are on the increase and strains that are resistant to all antimicrobials used to treat the disease have been found worldwide. These observations encouraged the World Health Organization to include Neisseria gonorrhoeae on their l...

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ग्रंथसूची विवरण
मुख्य लेखकों: Sanchez-Buso, L, Harris, SR
स्वरूप: Journal article
भाषा:English
प्रकाशित: Microbiology Society 2019
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author Sanchez-Buso, L
Harris, SR
author_facet Sanchez-Buso, L
Harris, SR
author_sort Sanchez-Buso, L
collection OXFORD
description <p style="text-align:justify;"> Gonorrhoea infections are on the increase and strains that are resistant to all antimicrobials used to treat the disease have been found worldwide. These observations encouraged the World Health Organization to include Neisseria gonorrhoeae on their list of high-priority organisms in need of new treatments. Fortunately, concurrent resistance to both antimicrobials used in dual therapy is still rare. The fight against antimicrobial resistance (AMR) must begin from an understanding of how it evolves and spreads in sexual networks. Genome-based analyses have allowed the study of the gonococcal population dynamics and transmission, giving a novel perspective on AMR gonorrhoea. Here, we will review past, present and future treatment options for gonorrhoea and explain how genomics is helping to increase our understanding of the changing AMR and transmission landscape. This article contains data hosted by <a href="https://microreact.org/project/rJQ6FGj8G" target="_blank">Microreact</a>. </p>
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spelling oxford-uuid:d22fe6c3-b718-4b5e-b775-24af39f5851b2022-03-27T08:02:09ZUsing genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeaeJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d22fe6c3-b718-4b5e-b775-24af39f5851bEnglishSymplectic Elements at OxfordMicrobiology Society2019Sanchez-Buso, LHarris, SR <p style="text-align:justify;"> Gonorrhoea infections are on the increase and strains that are resistant to all antimicrobials used to treat the disease have been found worldwide. These observations encouraged the World Health Organization to include Neisseria gonorrhoeae on their list of high-priority organisms in need of new treatments. Fortunately, concurrent resistance to both antimicrobials used in dual therapy is still rare. The fight against antimicrobial resistance (AMR) must begin from an understanding of how it evolves and spreads in sexual networks. Genome-based analyses have allowed the study of the gonococcal population dynamics and transmission, giving a novel perspective on AMR gonorrhoea. Here, we will review past, present and future treatment options for gonorrhoea and explain how genomics is helping to increase our understanding of the changing AMR and transmission landscape. This article contains data hosted by <a href="https://microreact.org/project/rJQ6FGj8G" target="_blank">Microreact</a>. </p>
spellingShingle Sanchez-Buso, L
Harris, SR
Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae
title Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae
title_full Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae
title_fullStr Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae
title_full_unstemmed Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae
title_short Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeae
title_sort using genomics to understand antimicrobial resistance and transmission in neisseria gonorrhoeae
work_keys_str_mv AT sanchezbusol usinggenomicstounderstandantimicrobialresistanceandtransmissioninneisseriagonorrhoeae
AT harrissr usinggenomicstounderstandantimicrobialresistanceandtransmissioninneisseriagonorrhoeae