Probing GPCR-Gα interactions: a functional study by EM and SPR

Probing GPCR-Gα interactions: a functional study by EM and SPR

<p>The G protein-coupled receptor (GPCR), neurotensin receptor type 1 (NTS1), is pharmacologically important and activated by the tridecapeptide hormone, neurotensin (NT), initiating a cascade of interactions through G proteins to effect cellular responses. The mechanisms by which these occur...

Bibliografske podrobnosti
Glavni avtor:	Adamson, RJ
Drugi avtorji:	Watts, A
Format:	Thesis
Jezik:	English
Izdano:	2014
Teme:	Microscopy Biochemistry Biophysics Molecular biophysics (biochemistry) Membrane proteins Biosensors Protein chemistry Nano-biotechnology

Podobne knjige/članki

Bioelectrochemistry by fluorescent cyclic voltammetry
od: Mizzon, G
Izdano: (2012)

Single-molecule DNA sensors and cages for transcription factors in vitro and in vivo
od: Crawford, R
Izdano: (2011)

The influence of environment: simulations of the influenza BM2 proton channel
od: Rouse, S
Izdano: (2012)

Structural studies of integrin activation
od: Anthis, N, et al.
Izdano: (2009)

Single molecule studies of a voltage-gated potassium channel
od: Angué, L
Izdano: (2013)

Computational studies of ligand-water mediated interactions in ionotropic glutamate receptors
od: Sahai, M
Izdano: (2011)

Protocol for real-time imaging of membrane fission by mitofissin
od: Tatsuro Maruyama, et al.
Izdano: (2023-12-01)

Structure and function of bacterial proteins secreted by the type three secretion and twin arginine translocation pathways
od: Lillington, J, et al.
Izdano: (2011)

Structural studies of cell surface signalling molecules for neuronal guidance and connectivity
od: Mitakidis, N
Izdano: (2013)

Imaging the assembly of the Staphylococcal pore-forming toxin alpha-Hemolysin
od: Thompson, J, et al.
Izdano: (2009)

Engineered α-hemolysin pores with chemically and genetically-fused functional proteins
od: Mantri, S
Izdano: (2013)

Engineered α-hemolysin pores with chemically and genetically-fused functional proteins
od: Mantri, S
Izdano: (2013)

Biophysical characterisation of self-assembling nanoparticles
od: Sawczyc, HLD
Izdano: (2020)

Protocol for evaluating drug-protein interactions based on fluorescence spectroscopy
od: Elaheh Jalali, et al.
Izdano: (2024-12-01)

Optimising protein synthesis in cell‐free systems, a review
od: Angelo C. Batista, et al.
Izdano: (2021-03-01)

Studying marcomolecular transitions by NMR and computer simulations
od: Stelzl, LS
Izdano: (2014)

Pushing the boundaries: molecular dynamics simulations of complex biological membranes
od: Parton, D
Izdano: (2011)

Mechanism of SigR inhibition by the anti-sigma factor RsrA from Streptomyces coelicolor
od: Francis, M, et al.
Izdano: (2015)

Interactions of Neisseria meningitidis with the human immune system
od: Harding, R
Izdano: (2015)

DNA origami assembly
od: Dunn, K, et al.
Izdano: (2014)

Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues
od: Labro, A, et al.
Izdano: (2008)

Molecular dissection of ionotropic glutamate receptor delta-family interactions with trans-synaptic proteins
od: Clay, J, et al.
Izdano: (2013)

Fluorescence studies of influenza RNA and RNA polymerase
od: Tomescu, A
Izdano: (2014)

A biophysical study of the G protein coupled receptor neurotensin receptor 1
od: Harding, PJ
Izdano: (2007)

Improving rapid affinity calculations for drug-protein interactions
od: Ross, G
Izdano: (2013)

Molecular characterisation of bacterial proteins that interact with sulfur or nitrogen compounds
od: Grabarczyk, D, et al.
Izdano: (2014)

Probing sulfatide-tissue lectin recognition with functionalized glycodendrimersomes
od: Paul V. Murphy, et al.
Izdano: (2021-01-01)

Molecular and structural characterisation of the human Fibrillin-1 N-C terminal interaction
od: Yadin, D
Izdano: (2013)

Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separation
od: Maria Vistrup-Parry, et al.
Izdano: (2021-11-01)

Monitoring GPCR conformation with GFP-inspired dyes
od: Anatoliy Belousov, et al.
Izdano: (2024-08-01)

Biophysical studies of membrane protein structure and function
od: Dijkman, P, et al.
Izdano: (2014)

Molecular dynamics study of water and Na⁺ ions in models of the pore region of the nicotinic acetylcholine receptor
od: Smith, G, et al.
Izdano: (1997)

The regulation and inhibition of P-TEFb
od: Hole, A
Izdano: (2011)

Structural studies of a membrane embedded chloride channel from E.Coli, a prokaryotic homologue of ClC channels
od: Bowler, M, et al.
Izdano: (2001)

Radiation damage in protein crystals examined under various conditions by different methods
od: Garman, E, et al.
Izdano: (2009)

Biophysical and magnetic resonance studies of membrane proteins
od: Orwick, M, et al.
Izdano: (2011)

Determination of X-ray flux using silicon pin diodes
od: Owen, R, et al.
Izdano: (2009)

An optogenetic proximity labeling approach to probe the composition of inducible biomolecular condensates in cultured cells
od: Emile Alghoul, et al.
Izdano: (2021-09-01)

Gαs slow conformational transition upon GTP binding and a novel Gαs regulator
od: Donghoon Ahn, et al.
Izdano: (2023-05-01)

Structural characterisation of the interaction between Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) and their human ligands in severe malaria
od: Ng, HK
Izdano: (2012)