Regulation of monoubiquitinated PCNA by DUB autocleavage.

Monoubiquitination is a reversible post-translational protein modification that has an important regulatory function in many biological processes, including DNA repair. Deubiquitinating enzymes (DUBs) are proteases that are negative regulators of monoubiquitination, but little is known about their r...

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Автори: Huang, T, Nijman, S, Mirchandani, K, Galardy, P, Cohn, M, Haas, W, Gygi, S, Ploegh, H, Bernards, R, D'Andrea, A
Формат: Journal article
Мова:English
Опубліковано: 2006