Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial.
BACKGROUND: Elderly and frail patients with cancer, although often treated with chemotherapy, are under-represented in clinical trials. We designed FOCUS2 to investigate reduced-dose chemotherapy options and to seek objective predictors of outcome in frail patients with advanced colorectal cancer....
Main Authors: | Seymour, M, Thompson, L, Wasan, H, Middleton, G, Brewster, A, Shepherd, S, O'Mahony, MS, Maughan, T, Parmar, M, Langley, R |
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Format: | Journal article |
Language: | English |
Published: |
2011
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