A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels.

A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels.

Microsomal triglyceride transfer protein (MTP) is required for the assembly and cellular secretion of apolipoprotein B (apoB) -containing lipoproteins from the liver and intestine. The secretion pattern of apoB-containing lipoproteins is likely to influence the VLDL and LDL levels in plasma. By init...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Karpe, F, Lundahl, B, Ehrenborg, E, Eriksson, P, Hamsten, A
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	1998

Παρόμοια τεκμήρια

Functional studies of a common promoter polymorphism in the microsomal triglyceride transfer protein gene (MTP)
ανά: Ehrenborg, E, κ.ά.
Έκδοση: (1999)

Postprandial plasma ApoB-48 levels are influenced by a polymorphism in the promoter of the microsomal triglyceride transfer protein gene.
ανά: Lundahl, B, κ.ά.
Έκδοση: (2002)

A common functional polymorphism in the promoter region of the MTP gene influences the plasma LDL level
ανά: Karpe, F, κ.ά.
Έκδοση: (1998)

Microsomal triglyceride transfer protein -493T variant reduces IDL plus LDL apoB production and the plasma concentration of large LDL particles.
ανά: Lundahl, B, κ.ά.
Έκδοση: (2006)

A functional polymorphism in the promoter region of the microsomal triglyceride transfer protein (MTP -493G/T) influences lipoprotein phenotype in familial hypercholesterolemia.
ανά: Björn Lundahl, κ.ά.
Έκδοση: (2000)

The effect of six polymorphisms in the microsomal triglyceride transfer protein (MTP) gene on distribution of LDL subtractions in healthy middle-aged men
ανά: Andersson, C, κ.ά.
Έκδοση: (2000)

Variants of the microsomal triglyceride transfer protein gene are associated with plasma cholesterol levels and body mass index.
ανά: Ledmyr, H, κ.ά.
Έκδοση: (2002)

Variants of the microsomal triglyceride transfer protein gene are associated with plasma cholesterol levels and body mass index
ανά: Helena Ledmyr, κ.ά.
Έκδοση: (2002-01-01)

Common variants in genes encoding plasma lipid-transfer and lipolytic proteins are associated with increased LDL particle size
ανά: Andersson, C, κ.ά.
Έκδοση: (2002)

The Ile128Thr polymorphism influences stability and ligand binding properties of the microsomal triglyceride transfer protein
ανά: H. Ledmyr, κ.ά.
Έκδοση: (2006-07-01)

The microsomal triglyceride transfer protein-493T allele confers increased risk of coronary heart disease
ανά: Ledmyr, H, κ.ά.
Έκδοση: (2002)

JTT-130, a microsomal triglyceride transfer protein (MTP) inhibitor lowers plasma triglycerides and LDL cholesterol concentrations without increasing hepatic triglycerides in guinea pigs
ανά: Shrestha Sudeep, κ.ά.
Έκδοση: (2005-09-01)

The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease.
ανά: Ledmyr, H, κ.ά.
Έκδοση: (2004)

Multiple functions of microsomal triglyceride transfer protein
ανά: Hussain M Mahmood, κ.ά.
Έκδοση: (2012-02-01)

Subcellular localization of microsomal triglyceride transfer protein
ανά: Larry L. Swift, κ.ά.
Έκδοση: (2003-10-01)

Identification of two polymorphisms in the promoter of the microsomal triglyceride transfer protein (MTP) gene: lack of association with lipoprotein profiles
ανά: Stefan-Martin Herrmann, κ.ά.
Έκδοση: (1998-12-01)

Loss of both phospholipid and triglyceride transfer activities of microsomal triglyceride transfer protein in abetalipoproteinemia
ανά: Irani Khatun, κ.ά.
Έκδοση: (2013-06-01)

A common promoter polymorphism affecting transcription of the MTP-gene influences lipoprotein phenotype in familial hypercholesterolaemia
ανά: Lundahl, B, κ.ά.
Έκδοση: (1998)

Intestinal fatty acid binding protein and microsomal triglyceride transfer protein polymorphisms in French-Canadian youth
ανά: Simona Stan, κ.ά.
Έκδοση: (2005-02-01)

Microsomal triglyceride transfer protein expression during mouse development
ανά: John M. Shelton, κ.ά.
Έκδοση: (2000-04-01)

Remnant lipoproteins are related to intima-media thickness of the carotid artery independently of LDL cholesterol and plasma triglycerides.
ανά: Karpe, F, κ.ά.
Έκδοση: (2001)

Effects of native, triglyceride-enriched, and oxidatively modified LDL on plasminogen activator inhibitor-1 expression in human endothelial cells.
ανά: Allison, B, κ.ά.
Έκδοση: (1999)

Remnant lipoproteins are related to intima-media thickness of the carotid artery independently of LDL cholesterol and plasma triglycerides
ανά: Fredrik Karpe, κ.ά.
Έκδοση: (2001-01-01)

Microsomal triglyceride transfer protein contributes to lipid droplet maturation in adipocytes.
ανά: Larry L Swift, κ.ά.
Έκδοση: (2017-01-01)

Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein
ανά: Narasimha Anaganti, κ.ά.
Έκδοση: (2022-09-01)

Novel mutations in the microsomal triglyceride transfer protein gene causing abetalipoproteinemia
ανά: Ken Ohashi, κ.ά.
Έκδοση: (2000-08-01)

A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein.
ανά: Meredith H Wilson, κ.ά.
Έκδοση: (2020-08-01)

Transfer of cholesteryl esters and phospholipids as well as net deposition by microsomal triglyceride transfer protein
ανά: Paul Rava, κ.ά.
Έκδοση: (2005-08-01)

Influence of common variants in the CETP, LPL, HL and APO E genes on LDL heterogeneity in healthy, middle-aged men.
ανά: Skoglund-Andersson, C, κ.ά.
Έκδοση: (2003)

Cardiac expression of microsomal triglyceride transfer protein is increased in obesity and serves to attenuate cardiac triglyceride accumulation.
ανά: Emil D Bartels, κ.ά.
Έκδοση: (2009-01-01)

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ανά: Narasimha Anaganti, κ.ά.
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ανά: Takashi Suzuki, κ.ά.
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ανά: M.Mahmood Hussain, κ.ά.
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ανά: Chuan-Ming Li, κ.ά.
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ανά: Humra Athar, κ.ά.
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ανά: Muhammad Tanveer Khan, κ.ά.
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Microsomal triglyceride transfer protein in CaCo-2 cells: characterization and regulation.
ανά: S N Mathur, κ.ά.
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Regulation of microsomal triglyceride transfer protein mRNA expression by endotoxin and cytokines
ανά: Miguel Navasa, κ.ά.
Έκδοση: (1998-06-01)

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ανά: Silveira, A, κ.ά.
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ανά: To Yuen Hui, κ.ά.
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