The in vivo rate of somatic adenomatous polyposis coli mutation.
Cancer arises through successive somatic mutations/epimutations of oncogenes and tumor-suppressor genes. Accurate estimates of the rates at which these (epi)mutations occur are a vital but missing link in our emerging quantitative understanding of tumorigenesis. Their absence has hindered arguments...
Κύριοι συγγραφείς: | , , |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2008
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