The in vivo rate of somatic adenomatous polyposis coli mutation.

Cancer arises through successive somatic mutations/epimutations of oncogenes and tumor-suppressor genes. Accurate estimates of the rates at which these (epi)mutations occur are a vital but missing link in our emerging quantitative understanding of tumorigenesis. Their absence has hindered arguments...

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Huvudupphovsmän: Hornsby, C, Page, K, Tomlinson, I
Materialtyp: Journal article
Språk:English
Publicerad: 2008