Ring-closing metathesis: novel routes to aromatic heterocycles.

Olefin metathesis has been established as an important and general reaction in synthetic organic chemistry. Recently, it has attracted interest as a powerful tool for the construction of aromatic heterocycles. The importance of heteroaromatic motifs in medicinal chemistry and biology, as well as the...

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Détails bibliographiques
Auteurs principaux: Donohoe, T, Fishlock, L, Procopiou, P
Format: Journal article
Langue:English
Publié: 2008
Description
Résumé:Olefin metathesis has been established as an important and general reaction in synthetic organic chemistry. Recently, it has attracted interest as a powerful tool for the construction of aromatic heterocycles. The importance of heteroaromatic motifs in medicinal chemistry and biology, as well as the efficiency and wealth of metathesis transformations, have resulted in significant success in this rapidly developing area.