Intravenous immunoglobulin in neurological disease: a specialist review.
Treatment of neurological disorders with intravenous immunoglobulin (IVIg) is an increasing feature of our practice for an expanding range of indications. For some there is evidence of benefit from randomised controlled trials, whereas for others evidence is anecdotal. The relative rarity of some of...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2002
|
| _version_ | 1797096578109931520 |
|---|---|
| author | Wiles, C Brown, P Chapel, H Guerrini, R Hughes, R Martin, T McCrone, P Newsom-Davis, J Palace, J Rees, J Rose, MR Scolding, N Webster, A |
| author_facet | Wiles, C Brown, P Chapel, H Guerrini, R Hughes, R Martin, T McCrone, P Newsom-Davis, J Palace, J Rees, J Rose, MR Scolding, N Webster, A |
| author_sort | Wiles, C |
| collection | OXFORD |
| description | Treatment of neurological disorders with intravenous immunoglobulin (IVIg) is an increasing feature of our practice for an expanding range of indications. For some there is evidence of benefit from randomised controlled trials, whereas for others evidence is anecdotal. The relative rarity of some of the disorders means that good randomised control trials will be difficult to deliver. Meanwhile, the treatment is costly and pressure to "do something" in often distressing disorders considerable. This review follows a 1 day meeting of the authors in November 2000 and examines current evidence for the use of IVIg in neurological conditions and comments on mechanisms of action, delivery, safety and tolerability, and health economic issues. Evidence of efficacy has been classified into levels for healthcare interventions (tables 1 and 2). |
| first_indexed | 2024-03-07T04:43:50Z |
| format | Journal article |
| id | oxford-uuid:d2929092-8527-40e6-a860-c62574f0f207 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:43:50Z |
| publishDate | 2002 |
| record_format | dspace |
| spelling | oxford-uuid:d2929092-8527-40e6-a860-c62574f0f2072022-03-27T08:04:54ZIntravenous immunoglobulin in neurological disease: a specialist review.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d2929092-8527-40e6-a860-c62574f0f207EnglishSymplectic Elements at Oxford2002Wiles, CBrown, PChapel, HGuerrini, RHughes, RMartin, TMcCrone, PNewsom-Davis, JPalace, JRees, JRose, MRScolding, NWebster, ATreatment of neurological disorders with intravenous immunoglobulin (IVIg) is an increasing feature of our practice for an expanding range of indications. For some there is evidence of benefit from randomised controlled trials, whereas for others evidence is anecdotal. The relative rarity of some of the disorders means that good randomised control trials will be difficult to deliver. Meanwhile, the treatment is costly and pressure to "do something" in often distressing disorders considerable. This review follows a 1 day meeting of the authors in November 2000 and examines current evidence for the use of IVIg in neurological conditions and comments on mechanisms of action, delivery, safety and tolerability, and health economic issues. Evidence of efficacy has been classified into levels for healthcare interventions (tables 1 and 2). |
| spellingShingle | Wiles, C Brown, P Chapel, H Guerrini, R Hughes, R Martin, T McCrone, P Newsom-Davis, J Palace, J Rees, J Rose, MR Scolding, N Webster, A Intravenous immunoglobulin in neurological disease: a specialist review. |
| title | Intravenous immunoglobulin in neurological disease: a specialist review. |
| title_full | Intravenous immunoglobulin in neurological disease: a specialist review. |
| title_fullStr | Intravenous immunoglobulin in neurological disease: a specialist review. |
| title_full_unstemmed | Intravenous immunoglobulin in neurological disease: a specialist review. |
| title_short | Intravenous immunoglobulin in neurological disease: a specialist review. |
| title_sort | intravenous immunoglobulin in neurological disease a specialist review |
| work_keys_str_mv | AT wilesc intravenousimmunoglobulininneurologicaldiseaseaspecialistreview AT brownp intravenousimmunoglobulininneurologicaldiseaseaspecialistreview AT chapelh intravenousimmunoglobulininneurologicaldiseaseaspecialistreview AT guerrinir intravenousimmunoglobulininneurologicaldiseaseaspecialistreview AT hughesr intravenousimmunoglobulininneurologicaldiseaseaspecialistreview AT martint intravenousimmunoglobulininneurologicaldiseaseaspecialistreview AT mccronep intravenousimmunoglobulininneurologicaldiseaseaspecialistreview AT newsomdavisj intravenousimmunoglobulininneurologicaldiseaseaspecialistreview AT palacej intravenousimmunoglobulininneurologicaldiseaseaspecialistreview AT reesj intravenousimmunoglobulininneurologicaldiseaseaspecialistreview AT rosemr intravenousimmunoglobulininneurologicaldiseaseaspecialistreview AT scoldingn intravenousimmunoglobulininneurologicaldiseaseaspecialistreview AT webstera intravenousimmunoglobulininneurologicaldiseaseaspecialistreview |