Therapeutic targeting of histone H3 lysine 36 trimethylation-deficient cancers
<p>Histone modifications play diverse and essential roles in the maintenance of genome integrity, as evidenced by the frequency at which different histone marks are dysregulated during tumourigenesis. The trimethylation of histone H3 at lysine 36 (H3K36me3) and SETD2, the enzyme solely respons...
المؤلف الرئيسي: | Lopez, K |
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مؤلفون آخرون: | Humphrey, T |
التنسيق: | أطروحة |
اللغة: | English |
منشور في: |
2019
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الموضوعات: |
مواد مشابهة
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The three methyls: the function and therapeutic potential of histone H3K36 trimethylation
حسب: Pfister, SX
منشور في: (2014) -
SMYD5 catalyzes histone H3 lysine 36 trimethylation at promoters
حسب: Yanjun Zhang, وآخرون
منشور في: (2022-06-01) -
Distribution and maintenance of histone H3 lysine 36 trimethylation in transcribed locus.
حسب: Henel Sein, وآخرون
منشور في: (2015-01-01) -
The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.
حسب: Klose, R, وآخرون
منشور في: (2006) -
Maternal Hyperglycemia Disrupts Histone 3 Lysine 36 Trimethylation of the IGF-1 Gene
حسب: Erin K. Zinkhan, وآخرون
منشور في: (2012-01-01)