Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5-HT1A autoreceptor in vivo.

1. It has been hypothesized that 5-HT1A autoreceptor antagonists may enhance the therapeutic efficacy of SSRIs and other antidepressants. Although early clinical trials with the beta-adrenoceptor/5-HT1 ligand, pindolol, were promising, the results of recent more extensive trials have been contradict...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Clifford, E, Gartside, SE, Umbers, V, Cowen, P, Hajós, M, Sharp, T
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 1998