Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5-HT1A autoreceptor in vivo.

1. It has been hypothesized that 5-HT1A autoreceptor antagonists may enhance the therapeutic efficacy of SSRIs and other antidepressants. Although early clinical trials with the beta-adrenoceptor/5-HT1 ligand, pindolol, were promising, the results of recent more extensive trials have been contradict...

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Những tác giả chính: Clifford, E, Gartside, SE, Umbers, V, Cowen, P, Hajós, M, Sharp, T
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 1998