Structure, function, and evolution of metallo-β-lactamases from the B3 subgroup-emerging targets to combat antibiotic resistance
β-Lactams are the most widely employed antibiotics in clinical settings due to their broad efficacy and low toxicity. However, since their first use in the 1940s, resistance to β-lactams has proliferated to the point where multi-drug resistant organisms are now one of the greatest threats to global...
Main Authors: | Krco, S, Davis, SJ, Joshi, P, Wilson, LA, Monteiro Pedroso, M, Douw, A, Schofield, CJ, Hugenholtz, P, Schenk, G, Morris, MT |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Frontiers Media
2023
|
Similar Items
-
Kinetic and structural characterization of the first B3 metallo-β-lactamase with an active-site glutamic acid
by: Wilson, LA, et al.
Published: (2021) -
Use of ferrous iron by metallo-β-lactamases.
by: Cahill, S, et al.
Published: (2016) -
Profiling interactions of vaborbactam with metallo-β-lactamases
by: Langley, G, et al.
Published: (2019) -
Interaction of Avibactam with Class B Metallo-β-Lactamases.
by: Abboud, M, et al.
Published: (2016) -
Cyclobutanone mimics of intermediates in metallo-β-lactamase catalysis.
by: Abboud, M, et al.
Published: (2017)