Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression.
BACKGROUND AND PURPOSE: In muscle-invasive bladder cancer there is an urgent need to identify relatively non-toxic radiosensitising agents for use in elderly patients. Histone deacetylase inhibitors radiosensitise tumour cells but not normal cells in vitro and variously downregulate DNA damage signa...
Main Authors: | Groselj, B, Kerr, M, Kiltie, A |
---|---|
פורמט: | Journal article |
שפה: | English |
יצא לאור: |
2013
|
פריטים דומים
-
Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression
מאת: Groselj, B, et al.
יצא לאור: (2013) -
The histone deacetylase inhibitor panobinostat as a radiosensitiser in bladder cancer
מאת: Groselj, B
יצא לאור: (2014) -
The HDAC Inhibitor Panobinostat Promotes Expression of Delta 133p53 Variants in TP53 Wild-type Bladder Cancer Cells
מאת: Groselj, B, et al.
יצא לאור: (2012) -
Differential Roles of Ku70 and Ku80 in the MMEJ Phenotype
מאת: Brideau, C, et al.
יצא לאור: (2012) -
Histone deacetylase inhibitors as radiosensitisers: Effects on DNA damage signalling and repair
מאת: Groselj, B, et al.
יצא לאור: (2013)